Role of iris changes as a cause of blindness in lepromatous leprosy.

Langerhans Cells in Skin Lesions of Leprosy

Background: Langerhans cells are important in the pathogenesis of leprosy.  A recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. Objective: To investigate a possible relationship between the number of Langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. Methods: An immunohistochemical staining for S100 prot...

Cataract surgery in the management of the late complications of lepromatous leprosy in South Korea.

Clinical examination of 113 patients in South Korea with lepromatous leprosy and severe visual impairment showed that the main cause of visual loss was the combined effect of corneal and lens opacities associated with small nonreacting pupils and iris atrophy. Cataract surgery with broad iridectomy and inferior sphincterotomy offers these patients with chronic lepromatous complications the best...

Electron Microscopic Study of Lepromatous Changes in the Iris.

Leprosy lesions of the fundus oculi.

OCULAR manifestations of leprosy constitute a very important aspect of the disease; the loss of vision, leading sometimes to ultimate blindness, may be as serious as any of the other manifestations of the.condition. The frequency of ocular involvement appears to vary greatly and estimates of its incidence vary from 10 to 100 per cent., but in Bengal ocular complications are probably less common...

Immune reconstitution inflammatory syndrome in an HIV seropositive leprosy patient.

The natural course of leprosy co-infected with human immunodeficiency virus (HIV) is not clearly understood. This is important because of the high and increasing prevalence of HIV infection in many leprosy endemic populations. – 3 The introduction of highly active antiretroviral therapy (HAART) has led to the emergence of a new clinical syndrome known as immune reconstitution inflammatory syndr...